A large subcutaneous nodule is located on the extensor surface of the forearm near the elbow. Rheumatoid nodules may be fixed or movable and are usually nontender. They occur most commonly at the elbow but may also be found on the feet, fingers, occiput, heels, and buttocks. Nodules occur in about 20% of patients with rheumatoid arthritis and are usually associated with high titers of rheumatoid factor. Subcutaneous nodules are also seen in other conditions such as systemic lupus erythematosus and mixed connective tissue disease.